Effects of an antiserum for epithelial-reticular cells of the thymus on T-dependent immune response
Premrov, M.G.; Mastino, A.; Favalli, C.
Bollettino della Societa Italiana di Biologia Sperimentale 59(11): 1665-1669
1983
ISSN/ISBN: 0037-8771 PMID: 6607737 Document Number: 212014
Relations between thymic factors and Prostaglandins (PG) were studied. We investigated on the effects of different incubation times with Thymosin Fraction 5 and Indomethacin on the release by spleen cells from normal or adult thymectomized mice. Prostaglandins were measured by radioimmunoassay. Thymosin induces an increase in PGE2 release on spleen cells obtained from thymectomized mice; the same effect was not observed on spleen cells obtained from normal mice.