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Small dose of ARA-C in the treatment of an elderly patient with acute myeloblastic leukemia

Takeyama, H.; Yano, K.; Ohoshima, K.; Satake, T.; Emi, N.; Sugihara, T.; Kawashima, K.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 10(11): 2418-2422

1983

ISSN/ISBN: 0385-0684
PMID: 6579883
Document Number: 211729
A 79 year old man with a history of myocardial infarction and cerebral infarction was admitted to our hospital in August, 1982. The hematological examination showed anemia and leukopenia (myeloblast 12%), and bone marrow aspiration confirmed the diagnosis of acute myeloblastic leukemia (FAB, M2). Because his general condition was poor, he was treated with small dose of Ara-C (10 mg/m2/12 hr, subcutaneous injections), obtaining complete remission. In cases of acute myeloblastic leukemia in elderly patients where other intensive treatments are contraindicated, it appears to be useful to employ a method of small dose of Ara-C therapy.

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