Hepatitis B infection and association with other sexually transmitted infections among men who have sex with men in Peru
Lama, J.R.; Agurto, H.S.; Guanira, J.V.; Ganoza, C.; Casapia, M.; Ojeda, N.; Ortiz, A.; Zamalloa, V.; Suarez-Ognio, L.; Cabezas, C.; Sanchez, J.L.; Sanchez, J.; Suarez, L.; Pun, M.; Cabezas, C.; Caballero, P.; Sanchez, J.; Lama, J.R.; Guanira, J.; Campos, P.; Lucchetti, A.; Goicochea, P.; Vergara, J.; Casapia, M.; Hinojosa, J.Carlos.; Zamalloa, V.; Ortiz, A.; Ojeda, N.; Tataje, A.; Garcia, P.; Carcamo, C.; Celum, C.L.; Holmes, K.K.; Zunt, J.; Whittington, W.; Hughes, J.P.; Sanchez, J.L.; Montano
American Journal of Tropical Medicine and Hygiene 83(1): 194-200
2010
ISSN/ISBN: 0002-9637 PMID: 20595501 DOI: 10.4269/ajtmh.2010.10-0003Document Number: 211630
To assess the epidemiology of hepatitis B virus (HBV) infection among men who have sex with men (MSM) in Peru, we evaluated the prevalence and associated risk factors for HBV serologic markers among participants of a HIV sentinel surveillance conducted in 2002-2003. The standardized prevalences for total antibodies to hepatitis B core antigen (anti-HBc) and hepatitis B surface antigen (HBsAg) were 20.2% and 2.8%, respectively. Individuals with human immunodeficiency virus (HIV-1) infection had significantly higher anti-HBc (44.3% versus 19.3%) and HBsAg (9.5% versus 2.3%) prevalences than uninfected men. Increasing age (adjusted odds ratio [AOR] = 1.06), versatile sexual role (AOR = 1.59), sex in exchange for money/gifts (AOR = 1.58), syphilis (AOR = 1.74), HIV-1 infection (AOR = 1.64), and herpes simplex virus type 2 (HSV-2, AOR = 2.77) infection were independently associated with anti-HBc positivity, whereas only HIV-1 infection (AOR = 3.51) and generalized lymph node enlargement (AOR = 3.72) were associated with HBsAg positivity. Pre-existing HBV infection is very common among Peruvian MSM and was correlated with sexual risk factors. MSM in Peru constitute a target population for further HBV preventive and treatment interventions.