Osteomedullary pathology in 5 cases of systemic mastocytosis. Pseudomyelomatous forms with dysglobulinemia and benign medullary polyclonal plasmacytosis. Hamazaki-Wesenberg Bodies associated with mast cell granuloma
Kermarec, J.; Canioni, D.; Zafisaona, G.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 59(29-30): 2119-2126
1983
ISSN/ISBN: 0037-1777 PMID: 6312584 Document Number: 210928
The authors describe bone marrow lesions in five cases of mastocytosis, with particular emphasis on the characteristic features of the infiltration of the mast cells, and the associated bone and medullary lesions. The five cases show two features not commonly encountered in the literature: the presence of seric dysglobulinemia with medullary polyclonal plasmacytosis in two cases; and the association of mast cells with Hamazaki-Wesenberg bodies in the other three. After recalling the actual mechanisms of bone lesions secondary to mast cell infiltration, the authors propose an explanation for the non-casual association of mastocytosis and Hamazaki-Wesenberg bodies, which has not been previously reported.