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Acute respiratory distress syndrome and lung fibrosis after ingestion of a high dose of ortho-phenylphenol

Cheng, S-Lung.; Wang, H-Chien.; Yang, P-Chyr.

Journal of the Formosan Medical Association 104(8): 585-587

2005

ISSN/ISBN: 0929-6646
PMID: 16193180
Document Number: 2105
Ordio-phenylplienol (OPP) and its sodium salt are used as fungicides and antibacterial agents, ingestion of which has been found to cause liver toxicity, renal toxicity and carcinomas in the urinary tract of rats. Lung damage due to OPP ingestion has not been reported in humans. We report a suicidal 39-year-old woman with stage 11 cervical cancer who drank a potentially lethal close of OPP in the loon of a commercial antiseptic, which led to the complication of liver and renal function impairment, severe long damage with acute respiratory distress syndrome and subsequent severe lung fibrosis. Open lung biopsy showed diffuse alveolar damage. She was discharged after 34 days of hospitalization with continuing domiciliary oxygen therapy.

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Acute respiratory distress syndrome and lung fibrosis after ingestion of a high dose of ortho-phenylphenol

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