Regulation of IgE antibody synthesis
Konig, W.; Pfeiffer, P.; Theobald, K.; Szperalski, B.; Voshaar, T.; Hess, K.H.; Bohn, A.
Allergologia et Immunopathologia 11(4): 277-284
1983
ISSN/ISBN: 0301-0546 PMID: 6228129 Document Number: 210220
It is well established that IgE-antibodies against allergens are involved in allergic diseases. Thus, the regulation of IgE antibody synthesis appears to be a fundamental approach to its treatment. The mechanisms of the IgE-antibody response are somehow different from IgG production. It appears that the immunocompetent cells involved are distinct and exert a different susceptibility with regard to IgE- and IgG antibody production. A more precise under-standing of the cellular processes involved in IgE-antibody production will lead to novel immunotherapeutic approaches of allergic disease processes.