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Molecular mechanism of combined effect of amphotericin B and cyclophosphamide on a virus-induced neoplastic process

Shneĭder, M.A.; Oksman, A.I.

Biulleten' Eksperimental'noi Biologii i Meditsiny 95(3): 63-66

1983

ISSN/ISBN: 0365-9615
PMID: 6299427
Document Number: 210145
Study of an experimental neoplastic process induced by virus type strains of Rous's sarcoma has shown that amphotericin B potentiates antineoplastic action of cyclophosphamide. Administration of cytostatin does not affect the fractional composition of chromatin proteins. Administration of polyene changes this indicator, the changes being greater after combined use of both drugs. The character of a considerable part of the abnormalities in the fractional composition of chromatin proteins indicates that chromatin had been exposed to proteolytic enzymes.

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Lu, L.J.; Randerath, K. 1984: Long term instability and molecular mechanism of 5-azacytidine-induced DNA hypomethylation in normal and neoplastic tissues in vivo Molecular Pharmacology 26(3): 594-603
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Zhdanov, V.M.; Chepulis, G.K.; Shevlyaghin, V.Y.; Mazurenko, N.P.; Kiselieva, L.G.; Zueva, J.N. 1973: The possibility to overcome species and age resistance in the induction of a neoplastic process by an avian tumour virus Revue Roumaine de Virologie 10(2): 161-168
Smida, J.; Smidová, V. 1977: Cyclophosphamide induced sensitivity against avian RNA myeloblastosis virus in age-resistant hosts Neoplasma 24(6): 595-600
Pruszewicz, A.; Obrebowski, A.; Kraśny, J. 1987: Effect of surgical factors, status of progression and the site of the neoplastic process on voice and speech rehabilitation after laryngectomy Otolaryngologia Polska 41(1-2): 147-157
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Urano, M.; Kim, M.S.; Kahn, J.; Kenton, L.A.; Li, M.L. 1985: Effect of thermochemotherapy (combined cyclophosphamide and hyperthermia) given at various temperatures with or without glucose administration on a murine fibrosarcoma Cancer Research 45(9): 4162-4166
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Emmerling, P.; Finger, H.; Henseling, M. 1973: The effect of high doses of antigen on cyclophosphamide-induced immunosuppression Arzneimittel-Forschung 23(1): 14-17
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