Surgery-related death, complicated wounds, and anastomosis healing in HIV-positive patients with considerable immune deficit: assumption and reality

Hájek, M.; Novák, K.; Zikmundová, K.

International Surgery 94(3): 228-236

2009


ISSN/ISBN: 0020-8868
PMID: 20187517
Document Number: 209823
This is to appreciate of truthness of predicate, that HIV-positive patients have, in most cases, the chance to develop postoperative complications and unsuccessful results. In the study, we assessed the experience of the first author in 3 years of expert work in Botswana, Southern Africa, and used nonparametric tests for statistical assessment of the results in those patients. In addition to clinical follow-up are patients assessed through study of CD4+ T lymphocytes and CD8+ T lymphocytes levels. Only in the most serious immunodeficiency group (Group C) were statistically important deviations in deaths and complications of wounds and anastomoses healing. For example, comparing HIV-positive patients and the HIV-negative population using a CD4+ T-lymphocyte level < 200 mm3, we can see the differences in the mortality rate: HIV-positive patients, 23.96%; HIV negative population 8.11%. The complication rate in HIV-positive patients with a CD4 level < 200 mm3 was 38.54% and in the HIV-negative population was 9.46%. The study disputes the myth that, in the majority of HIV-positive patients, we can expect limited surgical results and a larger rate of deaths and complications in wounds and anastomoses healing.

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