Env gene sequencing and HIV-1 subtyping of infected MSM from Beijing

Zhang, H.-H.; Sun, Y.; Liu, Y.-L.; Wu, Y.-S.; Dai, L.-L.; Wu, H.; Chen, D.-X.

Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 23(4): 275-277

2009


ISSN/ISBN: 1003-9279
PMID: 20108772
Document Number: 209491
To comprehend the latest HIV-I epidemic tendency and the character of V3 loop in MSM population of Beijing. METHODS; The C2-V3 regions of the HIV envelop gene were amplified by nest-PCR and sequenced from 11 HIV-l-infected MSM in Beijing in 2007. The subtype and sequences of V3 loop was analyzed. RESULTS There are 4 subtype B strains, 5 CRF AE, 1 CRFO7BC and 1 CRF15-01B strains within all 11 strains. There are five types of central motifs of the 11 samples, in which GPGR and GPGQ are most common. Recombination subtype of HIV-1 are spread extensively in MSM population of Beijing.

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