Incidence of HIV-1, syphilis, hepatitis B, and hepatitis C virus infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men in Beijing, China
Ruan, Y.; Jia, Y.; Zhang, X.; Liang, H.; Li, Q.; Yang, Y.; Li, D.; Zhou, Z.; Luo, F.; Shi, W.; Shao, Y.
Journal of Acquired Immune Deficiency Syndromes 52(5): 604-610
2009
ISSN/ISBN: 1944-7884 PMID: 19710617 DOI: 10.1097/qai.0b013e3181b31f5cDocument Number: 208788
To investigate the incidence of HIV-1, syphilis, hepatitis B virus (HBV), and hepatitis C virus (HCV) infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men (MSM) in Beijing, China. A total of 507 eligible seronegative MSM were enrolled. Study participants were tested for HIV-1, syphilis, HBV, and HCV and counseled at the baseline, 6-month, and 12-month follow-up visits. The retention rates were analyzed as a function of demographic, behavioral, and recruitment variables. Of the 507 participants, 86.2% (437) were retained in the cohort at the 12-month follow-up visit. The incidence rates were 2.6 per 100 person-years [95% confidence interval (CI): 1.1% to 4.1%] for HIV-1 infection, 16.9 per 100 person-years for syphilis (95% CI: 12.4% to 21.3%), 3.3 per 100 person-years for HBV (95% CI: 1.5% to 5.1%), and 0.2 per 100 person-years for HCV (95% CI: 0% to 0.7%). Higher education (adjusted odds ratio = 1.94, 95% CI: 1.03 to 3.66) and appearing at the 6-month follow-up visit (adjusted odds ratio = 26.15, 95% CI: 13.44 to 50.89) were significantly associated with 12-month retention. HIV, syphilis, and HBV incidence are high among MSM. Intensified intervention is needed urgently. Widespread screening for HIV, syphilis, HBV, and HCV in this group should be considered as measures for control.