Clinical use of ceftazidime in the field of obstetrics and gynaecology
Tateno, M.
Japanese Journal of Antibiotics 36(12): 3507-3516
1983
ISSN/ISBN: 0368-2781 PMID: 6371298 Document Number: 208649
Clinical effect and safety of ceftazidime (CAZ) in the obstetrics and gynaecology were studied in 7 cases of intrauterine infections, 8 cases of parametritis, 1 case of Bartholin's abscess, and 4 cases of intrapelvic infections totalling 20 cases. CAZ was administered at a dose of 2 g per day by intravenous drip infusion, for 4--9 days depending on severity of the disease. The results showed that CAZ was effective in 13 out of 20 cases (overall efficacy rate 65%), and especially in intrauterine infections, it was effective in all the cases. However, effects were not satisfactory in 8 cases of parametritis and 4 cases of intrapelvic infections for various reasons such as influences of underlying diseases including cancer. Neither adverse reactions nor abnormal laboratory findings attributable to CAZ were observed during the treatment.