Knowledge of and attitudes towards HIV/AIDS among school teachers in Belize
Lohmann, T.; Tam, P.; Hopman, W.M.; Wobeser, W.
International Journal of Infectious Diseases Ijid Official Publication of the International Society for Infectious Diseases 13(5): E228-E235
2009
ISSN/ISBN: 1201-9712 PMID: 19250849 DOI: 10.1016/j.ijid.2008.11.023Document Number: 208622
Some of the questions that have intrigued developmental biologists studying blood cell formation are: where do blood cells form, what are their precursors, and what signals are required for their emergence. Elegant embryonic grafting experiments in non-mammalian vertebrates, transplantation assays in mouse, and genetic analyses in zebrafish and mouse have been brought to bear on these problems, with enormous success. More recently investigators have applied conditional gene deletion and replacement strategies to refine our knowledge of this process in mammals. Here we describe several studies that have used the Cre/LoxP system to study blood cell formation, and what has been learned as a result.
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