The role of general practitioner research groups in the study of benzodiazepines
Harris, P.G.
L'Encephale 9(4 Suppl 2: 261b-265b
1983
ISSN/ISBN: 0013-7006 PMID: 6144522 Document Number: 208323
The advantages of a once a day regime of a long half life benzodiazepine are illustrated by a general pratitioner study in the U.K., which showed that in a group of over 100 patients, clorazepate 15 mg nocte was equally as effective as diazepam 5 mg three times a day. Another study carried out on 50 patients randomly allocated to lorazepam 1 mg t.d.s. or to clorazepate, which was directly related to the low incidence of side effects and simplicity of dosage.