Pericardial injury by antibacterial irrigants
Kratz, J.M.; Metcalf, J.S.; Sade, R.M.
Journal of Thoracic and Cardiovascular Surgery 86(5): 785-787
1983
ISSN/ISBN: 0022-5223 PMID: 6632954 Document Number: 204169
We injected antibacterial solutions into rabbit pericardium to investigate tissue injury. Povidone-iodine was the only irrigant found to cause substantial damage. These data lend experimental support to recent clinical observations that suggest a causal relation between pericardial irrigation with povidone-iodine and the later development of constrictive pericarditis.
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