Community perspectives on the ethical issues surrounding adolescent HIV vaccine trials in South Africa
Jaspan, H.B.; Soka, N.F.; Strode, A.E.; Mathews, C.; Mark, D.; Flisher, A.J.; Wood, R.; Bekker, L.-G.
Vaccine 26(45): 5679-5683
2008
ISSN/ISBN: 0264-410X PMID: 18782594 DOI: 10.1016/j.vaccine.2008.08.033Document Number: 203345
Adolescents globally are at high risk for HIV acquisition and are the targets of HIV prevention interventions such as HIV vaccines. In order to understand stakeholders' attitudes towards the ethical issues of adolescent involvement in HIV vaccine trials, we conducted focus group discussions with key members of a semi-urban, informal Cape Town community with high HIV prevalence in which HIV vaccine trials are taking place. Themes were identified from focus group transcripts by four researchers, and included necessity of guardian consent, age of independent consent, and confidentiality of in-trial medical results. In general, ethical adolescent HIV vaccine trials will be feasible in this community.
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