Topical ketorolac tromethamine in the reduction of adverse effects of laser in situ keratomileusist
Kosrirukvongs, P.; Prabhasawat, P.; Srivannaboon, S.; Pornpanich, K.
Journal of the Medical Association of Thailand 84(6): 804-810
2001
ISSN/ISBN: 0125-2208 PMID: 11556458 Document Number: 2031
Purpose: To evaluate whether topical ketorolac tromethamine can reduce the adverse effect of laser in situ keratomileusis (LASIK). Design: A prospective randomized controlled clinical study. Participants: Nineteen patients who underwent bilateral simultaneous LASIK performed at Siriraj Hospital. Intervention: Patients received two drops of ketorolac tromethamine in one eye immediately after surgery. Main Outcome Measures: Symptoms of tearing, photophobia, foreign body sensation and pain were evaluated at 30 minutes, 6 hours and 24 hours. Results: There was no statistically significant difference in symptoms at 30 minutes. At 6 and 24 hours, ketorolac-treated eyes had significantly fewer symptoms compared to non-treated eyes. Conclusions: Ketorolac tromethamine reduces some unfavorable symptoms within the first 24 hours after LASIK.
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