Measurement of the intensity of erythropoiesis based on the RNA content of erythrocytes
Osipova, S.N.; Mezhevikin, V.V.; Gitel'zon, I.I.
Biulleten' Eksperimental'noi Biologii i Meditsiny 96(7): 99-101
1983
ISSN/ISBN: 0365-9615 PMID: 6191798 Document Number: 203064
The relationship between RNA content in erythrocytes and the erythropoiesis rate was studied at varying exposures as a result of which a simple method for erythropoietic activity testing was proposed. It consists in the measurement of ribonucleic acid content in erythrocytes of mice with a decreased erythropoiesis after administration of the test sample. Erythropoietic activity is determined from the magnitude found. The method suggested is marked by simplicity and higher sensitivity and thus may be applied in clinical medicine and research.