Thyroid scintigraphy in children with hypothyroidism: a five-year experience
Pusuwan, P.; Likitmaskul, S.; Wacharasindhu, S.; Intarasupht, S.; Attanatho, V.; Mungkharak, J.; Chiewvit, S.; Pleehachinda, R.
Journal of the Medical Association of Thailand 81(8): 596-601
1998
ISSN/ISBN: 0125-2208 PMID: 9737112 Document Number: 2028
The presence or absence of thyroid glandular tissue demonstrated by thyroid scintigraphy is important for genetic and prognostic counseling and for acceleration of diagnosis in other affected siblings. Technetium-99m-pertechnetate thyroid scintigraphy was performed on 27 children with cretinism at the Division of Nuclear Medicine, Faculty of Medicine Siriraj Hospital during the 5-year period from June 1991. Based on scintigraphic findings, three main groups of thyroid localization were seen. Thirteen (48.1%) were athyrotic while 3 (11.1%) had an ectopic thyroid and 11 (40.8%) had gland in normal position. Perchlorate discharge test was performed in 8 children of the last group and the results were positive indicating an organification defect. Thyroid scintigraphy and perchlorate discharge test provided the useful information for diagnosis, follow-up, and prognosis in children with cretinism.
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