Impact of prolonged referral interval on colposcopic outcomes in women with moderate or severe dysplasia
Fakokunde, B.; Selo-Ojeme, D.
International Journal of Gynaecology and Obstetrics the Official Organ of the International Federation of Gynaecology and Obstetrics 101(3): 245-247
2008
ISSN/ISBN: 0020-7292 PMID: 18222448 DOI: 10.1016/j.ijgo.2007.11.014Document Number: 200974
To ascertain the impact of long referral to first colposcopy interval on disease outcome in women with high-grade cervical smear tests. Data from 316 women categorized into Group 1 (seen 180 days after referral) and Group 2 (seen within 180 days of referral) were analyzed using chi2 test with Yates correction. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. Women in Group 1 were less likely to need treatment (33.8% [25/74] vs 55.8% [135/242]; OR=0.45; 95% CI, 0.25-0.78; P=0.0004) and less likely to have high-grade disease (24.3% [18/74] vs 45.9% [111/242]); OR=0.37; 95% CI, 0.21-0.68; P=0.001) than women in Group 2. There was no significant difference between the groups in proportion of women with invasive disease. In women with high-grade smears the need for excisional treatment and the risk of invasive disease may be reduced by prolonged referral interval.
Document emailed within 0-6 h
