Cerebral blood flow and metabolism, and neurologic deficit in an experimental infarction. Application to the study of an ergot derivative
Cahn, J.; Borzeix, M.G.
Presse Medicale 12(48): 3058-3060
1983
ISSN/ISBN: 0755-4982 PMID: 6228914 Document Number: 199486
Both age and hypertension are risk factors for the brain. In the presence of a multiple cerebral infarction as obtained by the intra-carotid injection of sodium arachidonate, Hydergine is capable, in the young and old, hypertensive or normotensive rat, of limiting the extent of the edematous reaction, to prevent the intra-cerebral accumulation of Ca++ ions, and limit the fall in cerebral blood flow, all of these facts resulting in a significant improvement in neuromotor behaviour.