Computed tomography in hepatolenticular degeneration
Rachele, M.G.; Spallone, A.; Giagheddu, M.; Fiorini, S.; Silipo, P.
Acta Neurologica 5(1): 32-37
1983
ISSN/ISBN: 0001-6276 PMID: 6858737 Document Number: 198198
Fifteen cases of hepatolenticular degeneration have been studied by means of computerized cranial tomography (CT). The common abnormalities were hypodense areas in the regions of the basal ganglia, in 9 cases; ventricular dilatation, in 7 cases; cortical atrophy, in 5 cases and brain-stem atrophy, in 4 cases. CT abnormalities were most common and most marked in patients with neurological presentations, but 1 of 3 asymptomatic patients discovered by the genetic screening of the affected family had hypodense areas in bilateral lenticular nuclei.