Acute lymphoblastic leukemia with major eosinophilia. Inaugural cardiac insufficiency, endocarditis grafting and valve replacement
Bauters, F.; Jouet, J.P.; Huart, J.J.; Marcolin, M.; Fourrier, F.; Watel, A.
La semaine des hopitaux organe fonde par l'Association d'enseignement medical des hopitaux de Paris 59(22): 1679-1682
1983
ISSN/ISBN: 0037-1777 PMID: 6308790 Document Number: 197850
Acute lymphoblastic leukemia (cytologically typical) was diagnosed in an 18-year-old man presenting with major eosinophilia. Prednisone therapy was initiated but sudden congestive heart failure occurred (left ventricular insufficiency with pulmonary edema). Concomitantly, blood counts became normal. Remission of the leukemic process was obtained while severe mitral regurgitation developed, due to bacterial endocarditis. Successful mitral valvuloplasty was achieved. Remission is still persisting one year after diagnosis.