Eosinophilic meningitis in Hodgkin's disease. Report of a case and review of the literature
Hollister, D.; Clements, M.; Coleman, M.; Petito, F.
Archives of Internal Medicine 143(3): 590-592
1983
ISSN/ISBN: 0003-9926 PMID: 6338855 Document Number: 197096
Eosinophilic meningitis is rare in Hodgkin's disease. Five previous cases have been reported. We describe an additional patient whose CSF showed an eosinophilic pleocytosis with Reed-Sternberg cells while in complete systemic remission from Hodgkin's disease. The patient responded to intrathecal administration of methotrexate given by Ommaya reservoir. Six months later, systemic relapse occurred, but the CSF remained normal. Eosinophilic meningitis is a treatable complication of Hodgkin's disease, and prolonged response is possible.