Anorectic effect of SK and F 38393, a new dopamine agonist in rats
Girdhar, A.; Sharma, D.C.; Sachdev, K.S.
Indian Journal of Physiology and Pharmacology 26(4): 317-320
1982
ISSN/ISBN: 0019-5499 PMID: 6984016 Document Number: 196744
Anorectics are clinically used in the management of obesity to accept dietary restriction through decreased desire of food intake. The present study, indicates that the drug SK & F 38393 a dopamine agonist given to albino rats at the doses of 1 mg/kg and 5 mg/kg caused decreased food intake. Central side effects observed with amphetamine and other related drugs were not observed with this drug. The drug thus may be used as an anorectic agent without central side effects.