Changes in rat lymphoid tissue during ether and halothane anesthesia
Gusikhina, V.I.; Rudakov, V.F.; Ostroumova, M.N.; Frid, I.A.
Arkhiv Anatomii Gistologii i Embriologii 82(2): 87-91
1982
ISSN/ISBN: 0004-1947 PMID: 7082185 Document Number: 196686
A comparative quantitative investigation on the level of 11-oxycorticosteroids (11-OCS) in the peripheral blood and on morphological changes in the lymphoid tissue has been performed on intact and adrenalectomized rats after 3 hours' ether and halothane anesthesia. Three hours after the ether anesthesia, the level of 11-OCS increases more than twice, halothane is not a stress-producing anesthesia. After the ether anesthesia and essential devastation of the lymphoid tissue occurs, resulted from degeneration and a decreasing proliferative activity of the cells. In the adrenalectomized animals, both after halothane and either anesthesia, there are no essential morphological changes. Thus, certain significant differences between hormonal and morphological changes after either the halothane anesthesia have been revealed, as well as the role of the adrenal cortex in this activity.