Thrombolytic therapy for venous thrombosis in patients with gastro-intestinal diseases

Pogliani, E.M.; Bozzani, A.; Radaelli, F.; Conte, D.; Bardella, M.T.; Colombi, M.; Quatrini, M.

Pharmatherapeutica 3(4): 268-273

1982


ISSN/ISBN: 0308-051X
PMID: 6755491
Document Number: 196528
Venous thrombosis in 2 patients with gastro-intestinal diseases (chronic liver disease and ulcerative colitis) is reported. A good clinical improvement was obtained after thrombolytic (urokinase) therapy without any haemorrhagic side-effect. A decrease in the plasma of the fast-acting antiplasmin has been correlated with urokinase thrombolytic effect in vivo. These preliminary reports suggest that thrombolytic drugs are a safe tool for the treatment also of thromboembolic complications in patients with potential haemorrhagic diathesis.

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