Proliferative glomerulopathy in pneumococcal septicemia in a patient with lupus
Guillevin, L.; Janot, F.; Beaufils, H.; Godeau, P.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 58(20): 1221-1223
1982
ISSN/ISBN: 0037-1777 PMID: 6285506 Document Number: 196043
Acute glomerulopathy due to pneumococcal infection occurred in a patient with chronic discoid lupus. The onset of renal involvement in this context suggested that cutaneous lupus may have developed into systemic lupus erythematosus. Renal biopsy established the correct diagnosis. The physiopathology of glomerular involvement in lupus and infections is discussed. Attention is drawn to the significance of complement activation, either by the classical or the alternative pathways according to the etiology.