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PFC syndrome (persistent fetal circulation) . Central cyanosis in a full-term newborn infant without congenital heart defect

Schöber, J.G.; Bühlmeyer, K.

Fortschritte der Medizin 100(34): 1569-1572

1982

ISSN/ISBN: 0015-8178
PMID: 7129323
Document Number: 195016
In a case report the main features of the PFC-syndrome (persistent fetal circulation) are demonstrated: 1. general central cyanosis, 2. pulmonary hypertension, 3. right-to-left shunting via foramen ovale and (or) ductus arteriosus. At postmortem analysis in some of these patients the muscular thickness of the pulmonary vessels was found to be increased: primary PFC-syndrome. Hypoxia, shock, and many pulmonary disturbances of the newborn can produce the clinical picture of "persistent fetal circulation": secondary PFC-syndrome. Under adequate therapy with O2-insufflation, vasodilatory drugs, and if necessary mechanical ventilation the prognosis in the majority of cases is good.

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