Tumor-promoting phorbol esters and mezerien induce contraction in hydra

Shiba, Y.

Experientia 38(4): 498-499

1982


ISSN/ISBN: 0014-4754
PMID: 7084421
Document Number: 194896
12-O-tetradecanoyl phorbol-13-acetate (TPA, 1-100 ng/ml) induced a reversible contraction in the hydra, H. japonica. Another tumor-promoting phorbol ester, phorbol-12,13-didecanoate (PDD), and mezerein also induced contraction, but non-tumor-promoting derivatives such as 4.alpha.-PDD and phorbol did not.

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