Solid-phase radionuclide esophageal transit in progressive systemic sclerosis
Wang, S-Jen.; Lan, J-Liang.; Chen, D-Yuan.; Chen, Y-Hsing.; Hsieh, T-Yi.; Kao, C-Hung.; Lin, W-Yu.
Hepato-Gastroenterology 49(46): 989-991
2002
ISSN/ISBN: 0172-6390 PMID: 12143260 Document Number: 1936
Background/Aims: In most patients with progressive systemic sclerosis the esophagus is affected. Reflux symptoms are most frequent whilst dysphagia also occurs. The radionuclide esophageal transit study is a sensitive screening test for esophageal dysfunction. In this study, we evaluated the esophageal motility of patients with progressive systemic sclerosis using a solid-phase radionuclide esophageal study. Methodology: Thirty-two patients with progressive systemic sclerosis and 30 normal volunteers were studied with solid-phase radionuclide esophageal study. Each subject was placed in a supine position above a gamma camera linked to a computer and was given a 4-mL bolus of solid gelatin containing 1mCi of Tc-99m phytate. Data were acquired in the list mode. Results: Twenty-nine of the 32 patients (91%) had abnormal findings from the study. Conclusions: The radionuclide esophageal transit study can be regarded as a useful tool for evaluating the esophageal function in patients with progressive systemic sclerosis and in the follow-up of treatment.
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