Celiac disease, histocompatibility antigens and immunologic status
Boerr, L.A.; Morales, V.H.; Bai, J.C.; Gándara, M.A.; Barbatti, A.; Fink, N.; Morán, C.E.; Higa, R.A.
Acta Gastroenterologica Latinoamericana 12(4): 333-349
1982
ISSN/ISBN: 0300-9033 PMID: 7185231 Document Number: 193473
Researched from immunologic and genetic point of view, 40 patients with Celiac Diseases confirmed and under-treatment. The results were compared with a group of 257 healthy people. The immunologic studies: leucocytes and lymphocytes in blood, the subpopulation of lymphocytes T and B, The immune-reaction studies of immunoglobulin Ig G, Ig M, Ig A and component C III complement didn't show difference between the comparative groups justified perhaps because the group of patients were under-treatment. In the antigen erythrocyte A B O and RHO (A), we can only in those assert that there is an increase of A and B group between the patients than who have O, and they were less exposed to get the disease. Between the histocompatibility antigen, the low presence of A9 B5 B7 BW16 antigen in Celiac patients could be a sign of protection against the disease, contrarily the presence of A1 B8 Dr3 Dr7 could indicate the high risk to get the disease. These finding confirm that the antigen group connected with the major System of histocompatibility, showed the susceptibility to suffer the disease.