Hydromorphone detected in bile following hydrocodone ingestion

Park, J.I.; Nakamura, G.R.; Griesemer, E.C.; Noguchi, T.T.

Journal of Forensic Sciences 27(1): 223-224

1982


ISSN/ISBN: 0022-1198
PMID: 6178789
Document Number: 193342
Two similar cases are reported here in which Tussionex, a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.

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