Transient alteration of theophylline half-life: possible association with Herpes simplex infection
Anolik, R.; Kolski, G.B.; Schaible, D.H.; Ratner, J.
Annals of Allergy 49(2): 109-111
1982
ISSN/ISBN: 0003-4738 PMID: 7103148 Document Number: 192811
Transient alteration of theophylline half-life resulting in theophylline neurotoxicity is reported in a nine-year-old child. The alteration in theophylline elimination half-life was associated with Herpes simplex gingivostomatitis. This association has not previously been demonstrated. The report is contrasted with a study of theophylline clearance variability in children.
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