Dietary fibre and 10-year mortality from coronary heart disease, cancer, and all causes. The Zutphen study
Kromhout, D.; Bosschieter, E.B.; de Lezenne Coulander, C.
Lancet 2(8297): 518-522
1982
ISSN/ISBN: 0140-6736 PMID: 6125679 Document Number: 192442
In 1960, 871 middle-aged men in the town of Zutphen, The Netherlands, participated in a survey of risk indicators (including diet) for coronary heart disease (CHD). Information was collected about the usual food intake for the 6-12 mo. before the interview by the cross-check dietary history method. During 10 yr of follow-up, 107 men died from all causes, 37 from CHD and 44 from cancer. Mortality from CHD was .apprx. 4 times higher for men in the lowest quintile of dietary-fiber intake than for those in the highest quintile, but this inverse relation disappeared after multivariate analyses. Rates of death from cancer and from all causes were .apprx. 3 times higher for men in the lowest quintile of dietary-fiber intake than for those in the highest quintile, and these relations persisted after multivariate analyses. A diet containing at least 37 g dietary fiber per day may be protective against chronic diseases in Western societies.