Effects of N-demethylated carbachol on intraocular pressure and pupil in ocular hypertensive patients

Kitazawa, Y.; Shirato, S.

Japanese Journal of Ophthalmology 26(2): 224-228

1982


ISSN/ISBN: 0021-5155
PMID: 7131930
Document Number: 190974
The effects of N-demethylated carbachol on intraocular pressure and pupil size were studied in 18 ocular hypertensive patients. Topical administration of N-demethylated carbachol in 9%, 15% and 30% solutions has been demonstrated to bring about miosis which was found to be dose-dependent. No significant change of intraocular pressure clearly attributable to this drug has been demonstrated.

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