Immunochemical identification of ferritin and its immunological analogs beta-fetoprotein and alpha 2H-globulin
Prokopenko, P.G.
Biulleten' Eksperimental'noi Biologii i Meditsiny 93(4): 70-73
1982
ISSN/ISBN: 0365-9615 PMID: 6177357 Document Number: 190941
Immunochemistry techniques were made use of to identify the immunological analogs of ferritin - beta-fetoprotein and alpha 2H-globulin. Direct correlation of the test systems for ferritin, beta-fetoprotein and alpha-globulin demonstrated their complete identity. Electrophoretic mobility of beta-fetoprotein was found to be identical to that of ferritin, corresponding with blood serum alpha 2-globulins. alpha 2H-Globulin was obtained from human kidney tumors according to the method devised by the author. The glycoprotein component of alpha 2H-globulin isolated from the preparation alpha 2H-globulin did not prove identical to kidney tumor ferritin and was thus signed to serum alpha 2-macroglobulins of healthy subjects. Since there are no differences between ferritin and its immunological analogs, it is suggested that beta-fetoprotein and alpha 2H-globulin be termed ferritin.