Protein metabolic status of acute myocardial infarct patients before and after fentanyl and droperidol arrest of the pain syndrome
Kulikova, O.N.; Tarakanov, A.V.
Farmakologiia i Toksikologiia 45(4): 52-54
1982
ISSN/ISBN: 0014-8318 PMID: 7128786 Document Number: 190160
Protein fractions of the initial serum and acid-soluble proteins of the blood serum were examined in patients with acute myocardial infarction with marked pain syndrome before and after removal of the pain syndrome with fentanl and droperidol. It was noted that the total amount of protein in the initial serum and that of acid-soluble proteins were reduced as compared to the group of normal subjects. Disc electrophoresis demonstrated statistically significant differences in all the electrophoretic protein fractions of the initial blood serum. According to disc electrophoresis of acid-soluble proteins the greatest metabolic changes were experienced by proteins of the prealbumin zone. Three hours after the removal of the pain syndrome, protein metabolism did not return to normal. The intensity of quantitative changes in the disc electrophoretic zones remained at the same level as before the removal.