In vitro reactivity of natural killer (NK) cells against Cryptococcus neoformans

Murphy, J.W.; McDaniel, D.O.

Journal of Immunology 128(4): 1577-1583

1982


ISSN/ISBN: 0022-1767
PMID: 6120974
Document Number: 189627
The level of NK reactivity of the effector cell pools (unstimulated murine nylon wool-nonadherent splenic cells) using a 4 h 51Cr-release assay with YAC-1 targets correlated with the ability of effector cells to limit the growth of C. neoformans. It is suggested that NK cells may play a role in natural host defence in cryptococcosis.

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