Creatinephosphokinase and myoglobin monitoring in acute myocardial infarction
Pauletto, P.; Maddalena, F.; Scannapieco, G.; Vescovo, G.; Pessina, A.C.
International Journal of Tissue Reactions 4(2): 119-122
1982
ISSN/ISBN: 0250-0868 PMID: 7118172 Document Number: 187083
Creatinephosphokinase (CPK) and myoglobin (Mb) were measured in 15 patients admitted to the Coronary Care Unit for acute myocardial infarction (AMI). Blood samples were collected from the right atrium every six hours for 48 hours starting from the time of arrival in the Unit and were tested for CPK by a spectrophotometric technique and for Mb by an RIA method. Mb usually started to increase earlier than CPK and reached the peak plasma level more quickly. In five cases Mb but not CPK subsequently showed further increases during the course of the study. The suggestion is made that Mb measurements might be more reliable than CPK for the early detection and the initial followup of AMI.