Elevation of thermoregulatory vasodilatation threshold in the rat after capsaicin treatment
Obál, F.; Bari, F.; Benedek, G.; Obál, F.
Acta Physiologica Academiae Scientiarum Hungaricae 59(3): 203-207
1982
ISSN/ISBN: 0001-6756 PMID: 7168340 Document Number: 187043
In control and capsaicin-treated (300 mg/kg) rats tail skin vasodilatation was studied while the body temperature was raised to 38 degrees C, 39 degrees C or 40 degrees C and held at these levels. In the capsaicin-treated rats, at 38 degrees C vasodilatation was weaker than in the controls but at temperatures of 39 degrees C and 40 degrees C a delayed increase in tail vasodilatation occurred to the level observed in the controls. It is concluded that the threshold of vasodilatation response to heat is elevated after capsaicin treatment.