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Carbohydrate tolerance and intracellular sodium concentration in rabbits with dietary hypercholesterolemia

Gross, V.; Flemming, B.; Roloff, D.; Birkhahn, H.J.

Deutsche Zeitschrift für Verdauungs- und Stoffwechselkrankheiten 42(4): 169-176

1982

ISSN/ISBN: 0012-1053
PMID: 7128521
Document Number: 186027
The transport of sodium ions and glucose is a specialized membrane function. Variations in the cholesterol content of the cell membrane influence these functions. The influence of a hypercholesterolemia upon the intracellular sodium concentration and the glucose tolerance was investigated in cholesterol/rape oil and in cholesterol fed rabbits. The cholesterol/rape oil fed rabbits had lower KG-values and higher peripheral insulin levels than the control animals. The Na+Ery was decreased after 12 weeks of hypercholesterolemia. The na+Muscle was not changed. A negative correlation was found between the KG-value and the Na+Ery (Na+Muscle) in normal rabbits. In the hypercholesterolemic rabbits existed a negative correlation between the KG-value and the Na+Muscle and a positive correlation between the KG-value and the Na+Ery. It was postulated that membrane functions determined these correlations.

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Onizuka, S.; Kasaba, T.; Hamakawa, T.; Ibusuki, S.; Takasaki, M. 2004: Lidocaine increases intracellular sodium concentration through voltage-dependent sodium channels in an identified lymnaea neuron Anesthesiology 101(1): 110-120
Ratzmann, K.P.; Schulz, B.; Witt, S.; Heinke, P.; Michaelis, D. 1980: Spontaneous changes in carbohydrate tolerance and insulin secretion in persons with indications of disturbed carbohydrate tolerance. Preliminary results and follow-up observations for 7 years Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 35(6): 246-251
Wilson, R.B.; Newberne, P.M.; Conner, M.W. 1973: An improved semisynthetic atherogenic diet for rabbits. Dietary fat-carbohydrate interaction in atherogenesis Archives of Pathology 96(5): 355-359
Cameron, I.L.; Smith, N.K.; Pool, T.B.; Sparks, R.L. 1980: Intracellular concentration of sodium and other elements as related to mitogenesis and oncogenesis in vivo Cancer Research 40(5): 1493-1500
Deng, Y.; Yi, S.; Lin, Y.; Yan, J.; Guo, H.; Xiang, Z.; Wu, F.; Liu, W. 2007: Influence of needling the foot-yangming points on intracellular Ca2+ concentration in smooth muscles of the gastric antrum in rabbits Journal of Traditional Chinese Medicine 27(1): 65-69
Michaelis, O.E.; Carswell, N.; Velasquez, M.T.; Kimmel, P.L.; Abraham, A.A.; Canary, J.J.; Hansen, C.T. 1990: Influence of genetic obesity, dietary carbohydrate and age on parameters of glucose tolerance and kidney and adrenal gland histology in female SHR/N-corpulent rats International journal of obesity 14(11): 973-985
Wu, Y.J.; Li, X.F. 1991: Effects of sodium 18 beta-glycrrhetinic acid on the production of active oxygen species and the concentration of intracellular free Ca2+ in rat neutrophils Zhongguo Yao Li Xue Bao 12(3): 280-284
Wang, Z-jie.; Tian, X-zhi.; Li, X.; Chen, Z.; Zhao, L-cheng.; Zhou, B-fan.; Wu, Y-feng. 2005: Dietary treatment and success rate of control in hypercholesterolemia patients treated with lipid lowering drugs: a multi-center study of current status on clinical control of hypercholesterolemia in China Zhonghua Xin Xue Guan Bing Za Zhi 33(4): 372-375
Graczykowska-Koczorowska, A.; Ponikowska, I.; Bruszyńska, B.; Tycowa, M.; Kosowicz, J.; Porawska, J. 1980: The insulin level in the glucose tolerance test in patients with obesity and varying carbohydrate tolerance Przeglad Lekarski 37(2): 301-304
Andersen, D.B.; Holub, B.J. 1982: Effects of dietary cholesterol and type of dietary carbohydrate on hepatic and plasma glycerides and phospholipids in the gerbil Journal of Nutrition 112(7): 1425-1436
Andersen, M.M.; Ebbesen, K.; Hess, K.; Idorn, M.L.; Simonÿ, K. 1989: Dietary advice in hypercholesterolemia. Relation of selected dietary factors to total serum cholesterol and high density lipoprotein cholesterol Ugeskrift for Laeger 151(35): 2206-2210
Marakhova, I.I. 1984: Transmembrane effects in the sodium pump system. I. the effect of external potassium and rubidium on the dependence of sodium efflux on sodium concentration in the frog muscle Tsitologiia 26(10): 1136-1144
Manitius, J.; Kliz, J.; Krupa-Wojciechowska, B. 1985: The effect of dietary sodium loading on the kinetics of sodium excretion and blood pressure regulation in essential hypertensive men Cor et Vasa 27(1): 29-35
Fricker, J.; Douste-Blazy, P.; Drouin, P.; De Gennes, J.L.; Dachet, C.; Keller, U. 1990: The efficacy and tolerance of simvastatin and fenofibrate in primary hypercholesterolemia Presse Medicale 19(42): 1927-1930
Hansson, G.K.; Bondjers, G. 1980: Endothelial proliferation and atherogenesis in rabbits with moderate hypercholesterolemia Artery 7(4): 316-329
Sodi-Pollares, D. 1982: Theoretical effect in human heart disease of low-sodium high-potassium diet therapy on intracellular adsorbed sodium and potassium Physiological Chemistry and Physics 14(5): 439-443
Kocemba, J.; Kawecka-Jaszcz, K.; Sniezek, M. 1978: The oral glucose tolerance test in men with obesity, hypertension and hypercholesterolemia Przeglad Lekarski 35(4-5): 436-437
Titov, A.V.; Slobodskaia, V.V.; Tarasova, E.V.; Tereshin, I.M. 1981: Effect of cholesterol oxidase on the involution of experimental hypercholesterolemia in rabbits Voprosy Meditsinskoi Khimii 27(3): 345-349
Ishida, M.; Nakada, Y.; Horiuchi, M.; Sakamoto, F. 1998: Pharmacokinetics of danaparoid sodium, dalteparin sodium and heparin determined by inhibitory effect on the activated coagulation factor X activity after single intravenous administration in rabbits Arzneimittel-Forschung 48(8): 818-821
Dolgov, V.V.; Preobrazhenskiĭ, S.N.; Voĭno-Iasenetskaia, T.A.; Repin, V.S. 1982: Morphofunctional changes in the endothelial layer of the aorta and carotid artery in rabbits with hypercholesterolemia Arkhiv Patologii 44(11): 51-55