Effect of calmodulin inhibitor trifluoperazine on calcium activation of phosphorylase in glycosomes of rabbit skeletal muscles

Larionov, N.P.; Feoktistov, I.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 94(9): 35-36

1982


ISSN/ISBN: 0365-9615
PMID: 7171821
Document Number: 185707
Glycosomes isolated from rabbit skeletal muscles by acid precipitation and centrifugation, according to Fischer, show, in the presence of Ca, activation of phosphorylase which may be almost completely inhibited by 300 .mu.M trifluoroperazine. Flush-activation in glycosomes is apparently a calmodulin-dependent process.

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