Elevated level of urea is a good predictor for 30-day all-cause mortality in acutely admitted medical patients
Posth, S.; Anteskog, E.T.; Brabrand, M.
Acute Medicine 20(3): 174-181
2021
ISSN/ISBN: 1747-4892 PMID: 34679134 Document Number: 18182
To assess the correlation between urea and mortality in acutely ill medical patients admitted to hospital. We included consecutively admitted adult patients from the medical admission unit at a regional Danish hospital. Data on mortality was extracted. The association with 30-day mortality was described using cubic splines, and discriminatory power, crude association and adjusted analyses were performed. We included 5,894 patients, with a 30-day mortality of 5.6%. We found a dose-response relation between urea and 30-day mortality with an increase from 2.7% to 19.5% (p<0.001). Elevated urea is strongly associated with 30-day all-cause mortality in acutely admitted medical patients with acceptable discrimination and good calibration.
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