Juvenile and familial amyotrophic lateral sclerosis. 2 case reports
Saillant, A.; Fauchier, C.; Labarthe, J.C.; Despert, F.; Combe, P.
Archives Francaises de Pediatrie 38(4): 247-251
1981
ISSN/ISBN: 0003-9764 PMID: 7294951 Document Number: 179871
The case report of two brothers who evidenced neurological disorders with peripheral nerve syndrome, pyramidal deficit and bulbar symptoms is described. The diagnosis of amyotrophic lateral sclerosis was assumed upon the association of these clinical features. Seven and nine years respectively after the beginning of the disease, an increase of the clinical features was noticed in the 2 children, more pronounced in the second one. The possibility of true juvenile and familial amyotrophic lateral sclerosis is discussed in this study; different aspects of this disease are described. A final classification of these 2 cases will not be possible until histological features are available.