Specificity of tumor cell stimulation of DNA inhibitory cytokine production in vitro
Kieler, J.; Houssini, M.E.
Anticancer Research 1(4): 235-241
1981
ISSN/ISBN: 0250-7005 PMID: 7049051 Document Number: 179781
ST/a infected cells, evidence was obtained for the gp70 specificity of this stimulation. T-cell depletion by thymectomy and whole body irradiation caused a moderate reduction of the DNA inhibitory effect of the splenocyte culture supernatant. However, macrophage depletion by silicate caused an almost complete abolishment of DNA inhibitory cytokine production, which could not be restored by the addition of supplementary non-sensitized spleen cells.
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