Characterization of catecholamine binding sites in the rat brain
Agrawal, A.K.; Bondy, S.C.
Neurotoxicology 2(2): 365-371
1981
ISSN/ISBN: 0161-813X PMID: 6172758 Document Number: 179254
A systematic study of the effect of neurotoxic agents on neurotransmitter binding to specific receptors requires the simultaneous assay of several closely related ligand-receptor interactions. Conditions were presented which allowed the determination of dopaminergic, .alpha.-noradrenergic and .beta.-noradrenergic receptor sites within the same brain areas without major overlap of selectivity. As a result, regional distribution of catecholaminergic receptor sites and some characteristics of binding were described in rats.
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