Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature

Doerfler, L.; Hanke, C..William.

Journal of Drugs in Dermatology Jdd 18(7): 693-696

2019


ISSN/ISBN: 1545-9616
PMID: 31334929
Document Number: 17921
Keratoacathoma (KA) is a unique clinical pathological entity that is difficult to categorize. Differentiating a KA from a squamous cell carcinoma (SCC) is important for treatment implications but is often challenging. We report a patient with a solitary KA of the skin of the right ala successfully treated with intralesional (IL) injections of methotrexate (MTX). We also provide a review of the literature on IL-MTX as a treatment modality for KA.

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Treatment of Solitary Keratoacanthoma of the Nose With Intralesional Methotrexate and Review of the Literature