Prostaglandin F2 alpha and renal hypertension
Milanov, S.; Belovezhdov, N.; Milkov, V.; Gurev, I.; Kiperova, B.
Vutreshni Bolesti 20(6): 54-58
1981
ISSN/ISBN: 0506-2772 PMID: 6950590 Document Number: 179091
The values of PGf2 alpha were studied in 20 renal patients with renal hypertension, with and without chronic renal insufficiency via a radioimmunologic method. A control group of 10 healthy volunteers wer used without data from arterial hypertension. Values (672.0 +/- 99.5 pg/ml), being, with statistically significant difference, increased as compared with the healthy volunteers (347.13 +/- 49.9 pg/ml) were found in renal patients with chronic renal insufficiency. With the advancement of CRI in patients with renal hypertension, PG concentration was also increased (505.5 +/- 77.6 pg/ml) but it was not significant as in the patients without CRI. The elevated values of PGF2+ alpha suggest their participation in the pathogenesis of renal hypertension.