Gastrointestinal manifestations of cystic fibrosis: a review
Park, R.W.; Grand, R.J.
Gastroenterology 81(6): 1143-1161
1981
ISSN/ISBN: 0016-5085 PMID: 7026347 Document Number: 178263
Cystic fibrosis is a genetic syndrome of apparent exocrine dysfunction, characterized by obstructive lesions throughout multiple-organ systems and disturbances of mucus and electrolyte secretion. Cystic fibrosis is more common among white persons than among other racial groups. Pancreatic insufficiency in infants and children, meconium ileus, intestinal impaction and obstruction, rectal prolapse, hepatic abnormalities, nutritional deficiency, reduced appetite and slow growth rate are some of the manifestations of cystic fibrosis. Variations in manifestations among individual patients introduce additional burdens when assessing cause and treatment.