Sodium-glucose-cotransporter 2 inhibitor-associated euglycaemic diabetic ketoacidosis

Fisker, F.; Møller, N.; Lauritzen, E.S.

Ugeskrift for Laeger 181(21)

2019


ISSN/ISBN: 1603-6824
PMID: 31124439
Document Number: 17780
This case report describes a 51-year-old man, who had Type 2 diabetes and was being treated with a sodium-glucose-cotransporter 2 inhibitor (SGLT2i). The patient developed euglycaemic diabetic ketoacidosis (DKA) during surgery. A perioperative arterial blood gas analysis revealed meta-bolic acidosis (pH = 7.07), but the euglycaemic component of the DKA resulted in a delayed diagnosis of the DKA by 12 hours. A delayed diagnosis of DKA can be fatal, thus em-phasising the importance of considering DKA as a dif-erential diagnosis in SGLT2i-treated patients with unspecific symp-toms.

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Sodium-glucose-cotransporter 2 inhibitor-associated euglycaemic diabetic ketoacidosis